Trimethylacetic anhydride

CAS No.: 1538-75-6

Synonyms: Pivalic anhydride;

Bis(2,2-dimethylpropionic)anhydride;Pivalicanydride;Bis(pivalic)anhydride;Pivalicacidanhydride;2,2-DimethylpropaChemicalbooknoicanhydride;2,2-dimethylpropanoyl2,2-dimethylpropanoate;Dipivalicanhydride;PivalicAnhydride>Trimethylaceticanhy

CBNumber: CB9470666

Molecular formula: C10H18O3

Molecular weight: 186.25

Form: Liquid

Color: Clear colorless

Packaging:180kg/drum;

Uses Trimethylacetic anhydride is a metabolite of ganciclovir's biprodrug (6-dGCV-DPiv).

Synthetic uses Pivalic anhydride is used as an acylation and esterification reagent.

It participates in the acylation and esterification reactions with aniline and phenol. 

Trimethyl acetic anhydride is also used in solid phase oligonucleotide synthesis and kinetic resolution of racem-2-hydroxy-γ-butyllactone and diphenylacetic acid to produce cyano-4, n-tert-butyloxycarbonpiperidine, and also used in solid phase oligonucleotide synthesis.